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| Low-Fat vs Low-Carbohydrate Diet on Weight Loss in Overweight Adults Question What is the effect of a healthy low-fat (HLF) diet vs a healthy low-carbohydrate (HLC) diet on weight change at 12 months and are these effects related to genotype pattern or insulin secretion? Findings In this randomized clinical trial among 609 overweight adults, weight change over 12 months ...
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