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	in As-it-happens update ⋅ 5 February 2026
	NEWS
	Kras G12C– and G12D–driven lung cancers differ in oncogenic potency, immunogenicity ... - Science Science Our findings underscore key differences between KRAS G12D and G12C mutations in shaping lung cancer biology, reveal distinct resistance dynamics under ... Flag as irrelevant
	PtdIns(3,5)P2 is an endogenous ligand of STING in innate immune signalling | Nature Nature Deletion of PIKFYVE blocked STING trafficking from the ER and TBK1 activation. In vitro reconstitution uncovered a strong and selective effect of ... Flag as irrelevant
	Storm Leonardo hits Iberian peninsula: One dead in Portugal, thousands forced to evacuate in Spain YouTube Torrential rainfall of up to 40 centimetres in just 24 hours has battered the Iberian Peninsula, much of it already waterlogged by earlier winter ... Flag as irrelevant

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